Network Effects and Diffusion in Pharmaceutical Markets: Antiulcer Drugs

Working Paper: NBER ID: w7024

Authors: Ernst R. Berndt; Robert S. Pindyck; Pierre Azoulay

Abstract: We examine the role of network effects in the demand for pharmaceuticals at both the brand level and for a therapeutic class of drugs. These effects emerge when use of a drug by others conveys information about its efficacy and safety to patients and physicians. This can lead to herd behavior where a particular drug -- not necessarily the most efficacious or safest -- can come to dominate the market despite the availability of close substitutes, and can also affect the rate of market diffusion. Using data for H2-antagonist antiulcer drugs, we examine two aspects of these effects. First, we use hedonic price procedures to estimate how the aggregate usage of a drug affects brand valuation. Second, we estimate discrete-time diffusion models at both the industry and brand levels to measure the impact on rates of diffusion and market saturation.

Keywords: network effects; pharmaceutical markets; antiulcer drugs; demand diffusion

JEL Codes: D12; L65


Causal Claims Network Graph

Edges that are evidenced by causal inference methods are in orange, and the rest are in light blue.


Causal Claims

CauseEffect
aggregate usage of a drug (C43)brand valuation (M37)
past sales (D44)rate of diffusion of a drug (C22)
aggregate usage of a drug (C43)perceived efficacy and safety (D18)
perceived efficacy and safety (D18)brand valuation (M37)
past sales (D44)accelerated adoption rates (D16)
awareness and word-of-mouth communication (O36)diffusion process (O33)

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