Which Markets Don’t Drive Pharmaceutical Innovation? Evidence from US Medicaid Expansions

Working Paper: NBER ID: w28755

Authors: Craig Garthwaite; Rebecca Sachs; Ariel Dora Stern

Abstract: Pharmaceutical innovation policy involves managing a tradeoff between high prices for new products in the short-term and stronger incentives to develop products for the future. Prior research has documented a causal relationship between market size and pharmaceutical research and development (R&D) activities. The existing literature, however, provides no evidence of how this relationship varies across markets. We investigate whether recent expansions in state Medicaid programs caused an increase in R&D. We find no evidence of a response, potentially a result of Medicaid’s low reimbursement for pharmaceuticals, suggesting low(er) price markets may have different dynamics with respect to innovation policy.

Keywords: pharmaceutical innovation; Medicaid expansions; R&D investments; market size

JEL Codes: H01; I43; L53; O38


Causal Claims Network Graph

Edges that are evidenced by causal inference methods are in orange, and the rest are in light blue.


Causal Claims

CauseEffect
Medicaid expansions (I18)R&D investments (O32)
Market size (L25)R&D investments (O32)
Lower reimbursement rates (I13)R&D investments (O32)
Medicaid expansions (I18)Anticipated increase in demand (J23)
Medicaid expansions (I18)No change in R&D activities (O39)
Medicare Part D expansions (H51)R&D investments (O32)

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