Can Policy Affect Initiation of Addictive Substance Use? Evidence from Opioid Prescribing

Working Paper: NBER ID: w25974

Authors: Daniel W. Sacks; Alex Hollingsworth; Thuy D. Nguyen; Kosali I. Simon

Abstract: Drug control policy can have unintended consequences by pushing existing users to alternative, possibly more dangerous substances. Policies that target only new users may therefore be especially promising. Using commercial insurance claims data, we provide the first evidence on a set of new policies intended to reduce opioid initiation in the form of limits on initial prescription length. We also provide the first evidence on the impact of must-access prescription drug monitoring programs (MA-PDMPs), laws that do not target new users, on initial opioid use. Although initial limit policies reduce the average length of initial prescriptions, they do so primarily by raising the frequency of short prescriptions, resulting in increases in opioids dispensed to new users. In contrast, we find that MA-PDMPs reduce opioids dispensed to new users, even though they do not explicitly set out to do so. Neither policy significantly affects extreme use such as doctor shopping among new patients, because such behavior is very rare.

Keywords: opioids; prescribing; addiction; policy; public health

JEL Codes: I12; I18


Causal Claims Network Graph

Edges that are evidenced by causal inference methods are in orange, and the rest are in light blue.


Causal Claims

CauseEffect
initial prescription limits (Y20)hazard of new prescriptions (I19)
MAPDMPS (C69)hazard of initial prescriptions (I12)
initial prescription limits (Y20)amount of opioids dispensed to new users (D30)
MAPDMPS (C69)new opioid use (I12)

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