A Randomized Controlled Behavioral Intervention to Promote Walking After Abdominal Organ Transplantation: Results from the LIFT Study

Working Paper: CEPR ID: DP14420

Authors: Marina Serper; Iwan Barankay; Sakshum Chadha; Justine Shults; Lauren S. Jones; Kim Olthoff; Peter Reese

Abstract: Kidney transplant recipients (KTRs) and liver transplant recipients (LTRs) have significant post-transplant weight gain and low physical activity. We conducted a home-based, remotely-monitored intervention using wearable accelerometer devices to promote post-transplant physical activity. We randomized 61 KTRs and 66 LTRs within 24 months of transplant to: 1) control, 2) accelerometer, or 3) intervention: accelerometer paired with financial incentives and health engagement questions to increase steps by 15% from baseline every 2 weeks. The primary outcome was weight change. A co-primary outcome for the two accelerometer arms was steps. Participants were recruited at a median of 9.5 [3-17] months post-transplant. At 3 months, there were no significant differences in weight change across the 3 arms. The intervention arm was more likely to achieve ≥7000 steps compared to control with device (OR 1.99, 95% CI:1.03-3.87); effect remained significant after adjusting for demographics, allograft, time from transplant, and baseline weight. Adherence to target step goals was 74% in the intervention arm, 84% of health engagement questions were answered correctly. A pilot study with financial incentives and health engagement questions was feasible and led KTRs and LTRs to walk more, but did not affect weight. A definitive trial is warranted. (ClinicalTrials.gov number: NCT03221465).

Keywords: physical activity; behavior change; remote monitoring; self-care; behavioral economics; exercise

JEL Codes: No JEL codes provided


Causal Claims Network Graph

Edges that are evidenced by causal inference methods are in orange, and the rest are in light blue.


Causal Claims

CauseEffect
adherence to step goals (L21)weight change (F31)
intervention arm (with accelerometer and financial incentives) (O31)likelihood of achieving the target of 7000 steps (Y10)
increased physical activity (I12)weight management (L21)

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